CBLL1

Across TCGA cell cohorts, CBLL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,528 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CBLL1-associated GO terms across cancer lineages are Regulation of telomeric D-loop disassembly, Positive regulation of t-circle formation, and Heterochromatin formation. Each is linked with CBLL1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CBLL1-to-partner and partner-to-CBLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomeric D-loop disassembly grouped by CBLL1-low versus CBLL1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLL1→partner) and Y-score (partner→CBLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of telomeric D-loop disassembly →	+0.122	+1.146	<.001	<.001	3	13
LARGE_INTESTINE	Positive regulation of t-circle formation →	-0.180	-0.601	<.001	<.001	3	11
SOFT_TISSUE	Heterochromatin formation →	+0.066	+0.874	<.001	.001	3	11
LUNG_NSCLC_LUAD	Positive regulation of DNA recombination →	+0.058	+0.460	<.001	.005	3	11
BONE	Positive regulation of isotype switching to IgG isotypes →	+0.174	+0.740	<.001	.002	3	11
BREAST	Peptidyl-glutamic acid carboxylation →	+0.106	+0.812	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,528 associations by consensus.

Regulation of telomeric D-loop disassembly by CBLL1 expression — OVARY

Explore this box plot interactively →