CBLC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CBLC RNA expression is significantly associated with the protein abundance of many other proteins, with 11,592 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CBLC-associated proteins across cancer lineages are PNKP, PRKACB, and UTP18_S210. Each is linked with CBLC in more than 4 cancer types. Because this analysis shows association rather than direction, both CBLC-to-partner and partner-to-CBLC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBLC versus PNKP in COAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLC→partner) and Y-score (partner→CBLC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPNKP →+0.210+0.357<.001.00435
BRCAPRKACB →-0.423-0.890.003.00635
LSCCUTP18_S210 →+0.595+1.063.003.00234
LSCCUTP4 →+0.289+0.991.004<.00134
HNSCCTBP1 →-0.226-0.778<.001<.00134
LUADDDX21_S121 →+0.695+0.761<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,592 associations by consensus.

CBLC vs PNKP — COAD

Per-sample scatter of CBLC vs PNKP in COAD (Pearson r = 0.34).

Explore this scatter interactively →

Exploration