CBLC

Across TCGA cell cohorts, CBLC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,296 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CBLC-associated GO terms across cancer lineages are Maintenance of blood-brain barrier, Bundle of His cell to Purkinje myocyte communication, and Regulation of cardiac muscle cell action potential. Each is linked with CBLC in more than 10 cancer types. Because this analysis shows association rather than direction, both CBLC-to-partner and partner-to-CBLC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of blood-brain barrier grouped by CBLC-low versus CBLC-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLC→partner) and Y-score (partner→CBLC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Maintenance of blood-brain barrier →	+0.214	+3.399	<.001	<.001	3	11
OVARY	Bundle of His cell to Purkinje myocyte communication →	+0.463	+3.396	<.001	<.001	3	11
STOMACH	Regulation of cardiac muscle cell action potential →	+0.180	+3.979	<.001	<.001	3	11
URINARY_TRACT	Serotonin secretion →	+1.516	+3.172	<.001	.001	3	10
BREAST	Regulation of potassium ion import →	+0.175	+2.095	<.001	.004	3	10
URINARY_TRACT	Serotonin production involved in inflammatory response →	+1.516	+3.172	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,296 associations by consensus.

Maintenance of blood-brain barrier by CBLC expression — STOMACH

Explore this box plot interactively →