CBLC

Across TCGA cell cohorts, CBLC mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CBLC-associated genes across cancer lineages are GSK1904529A, 123138, and NSC-207895. Each is linked with CBLC in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLC-to-partner and partner-to-CBLC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK1904529A grouped by CBLC-low versus CBLC-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLC→partner) and Y-score (partner→CBLC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK1904529A →	+0.381	+2.900	.015	.015	3	1
LARGE_INTESTINE	123138 →	+0.293	+2.871	.037	.021	3	1
LARGE_INTESTINE	NSC-207895 →	+0.689	+2.914	<.001	.012	3	1
LARGE_INTESTINE	Ara-G →	+0.185	+2.944	.020	.018	2	1
LARGE_INTESTINE	IRAK4_4710 →	+0.547	+2.871	.001	.021	1	1
LARGE_INTESTINE	JAK1_8709 →	+0.477	+2.871	.010	.021	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GSK1904529A by CBLC expression — LARGE_INTESTINE

Explore this box plot interactively →