CBLB

Across TCGA patient cohorts, CBLB RNA expression is significantly associated with the protein abundance of many other proteins, with 10,493 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CBLB-associated proteins across cancer lineages are CBLB_S634, CLPX, and DAPK3. Each is linked with CBLB in more than 5 cancer types. Because this analysis shows association rather than direction, both CBLB-to-partner and partner-to-CBLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBLB versus CBLB_S634 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLB→partner) and Y-score (partner→CBLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CBLB_S634 →	+0.822	+0.314	<.001	<.001	3	6
LUAD	CLPX →	-0.262	-0.464	<.001	<.001	3	5
BRCA	DAPK3 →	+0.360	+0.416	<.001	.001	3	5
PDAC	TLN1 →	+0.314	+0.384	<.001	<.001	3	5
BRCA	MMP2 →	+0.651	+0.465	<.001	<.001	3	4
PDAC	PRRX1 →	+0.661	+0.374	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,493 associations by consensus.

CBLB vs CBLB_S634 — PDAC

Explore this scatter interactively →