CBL

Across TCGA patient cohorts, CBL protein abundance is significantly associated with the RNA expression of many other genes, with 13,648 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBL-associated genes across cancer lineages are TLR8, ETS1, and LINC00528. Each is linked with CBL in more than 6 cancer types. Because this analysis shows association rather than direction, both CBL-to-partner and partner-to-CBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBL versus TLR8 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBL→partner) and Y-score (partner→CBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TLR8 →	+1.001	+0.208	<.001	.004	3	7
CCRCC	ETS1 →	+0.619	+0.160	<.001	<.001	3	7
LSCC	LINC00528 →	+0.484	+0.152	<.001	<.001	3	7
UCEC	TNFRSF1B →	+0.893	+0.211	<.001	.001	3	7
UCEC	LCP2 →	+0.805	+0.238	.002	<.001	3	7
UCEC	CSF2RB →	+1.015	+0.216	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,648 associations by consensus.

CBL vs TLR8 — UCEC

Explore this scatter interactively →