CBFA2T3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CBFA2T3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,693 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CBFA2T3-associated genes across cancer lineages are PLCH2, PCOLCE, and CNTNAP1. Each is linked with CBFA2T3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CBFA2T3-to-partner and partner-to-CBFA2T3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBFA2T3 versus PLCH2 in LSCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBFA2T3→partner) and Y-score (partner→CBFA2T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPLCH2 →+1.089+1.344<.001<.00133
UCECPCOLCE →+1.220+1.136.009.00132
UCECCNTNAP1 →+0.731+1.074<.001.00132
CCRCCPCDH12 →+1.208+0.936<.001<.00132
UCECKREMEN2 →+0.941+1.153.001.00132
HNSCESPNL →+0.964+1.301.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,693 associations by consensus.

CBFA2T3 vs PLCH2 — LSCC

Per-sample scatter of CBFA2T3 vs PLCH2 in LSCC (Pearson r = 0.38).

Explore this scatter interactively →

Exploration