CBFA2T3

Across TCGA cell cohorts, CBFA2T3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,698 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CBFA2T3-associated GO terms across cancer lineages are Regulation of plasminogen activation, Regulation of transcription initiation by RNA polymerase II, and Nucleic acid catabolic process. Each is linked with CBFA2T3 in more than 8 cancer types. Because this analysis shows association rather than direction, both CBFA2T3-to-partner and partner-to-CBFA2T3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasminogen activation grouped by CBFA2T3-low versus CBFA2T3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBFA2T3→partner) and Y-score (partner→CBFA2T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of plasminogen activation →	-0.262	-1.075	<.001	<.001	3	9
BLOOD_Lymphoma	Regulation of transcription initiation by RNA polymerase II →	+0.062	+2.149	<.001	<.001	3	8
BLOOD_Lymphoma	Nucleic acid catabolic process →	+0.047	+2.720	<.001	<.001	3	8
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.076	+1.202	<.001	<.001	3	8
SOFT_TISSUE	Aldosterone biosynthetic process →	+1.216	+0.779	<.001	<.001	3	8
BREAST	Primary alcohol biosynthetic process →	-0.231	-2.015	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,698 associations by consensus.

Regulation of plasminogen activation by CBFA2T3 expression — SOFT_TISSUE

Explore this box plot interactively →