CBFA2T3

Across TCGA cell cohorts, CBFA2T3 mutation is significantly associated with the RNA expression of many other genes, with 531 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CBFA2T3-associated genes across cancer lineages are KRTAP20-2, CSNKA2IP, and C1orf198. Each is linked with CBFA2T3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBFA2T3-to-partner and partner-to-CBFA2T3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP20-2 grouped by CBFA2T3-low versus CBFA2T3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBFA2T3→partner) and Y-score (partner→CBFA2T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	KRTAP20-2 →	+0.072	+4.369	<.001	.008	3	2
OESOPHAGUS	CSNKA2IP →	+0.036	+4.906	<.001	.006	3	2
LARGE_INTESTINE	C1orf198 →	+0.607	+2.502	.009	.005	3	2
LARGE_INTESTINE	STOX1 →	+1.071	+2.502	<.001	.005	3	2
LARGE_INTESTINE	PDIK1L →	+0.740	+3.628	<.001	<.001	3	2
LARGE_INTESTINE	HSF2 →	+0.545	+2.502	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 531 associations by consensus.

KRTAP20-2 by CBFA2T3 expression — SOFT_TISSUE

Explore this box plot interactively →