CBFA2T2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CBFA2T2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,302 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBFA2T2-associated genes across cancer lineages are HBA2, SNORA33, and HBA1. Each is linked with CBFA2T2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CBFA2T2-to-partner and partner-to-CBFA2T2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBFA2T2 versus HBA2 in OV, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBFA2T2→partner) and Y-score (partner→CBFA2T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVHBA2 →+2.649+1.793<.001<.00133
OVSNORA33 →+0.875+1.371.001.00232
CCRCCHBA1 →+1.593+1.783.004.00732
OVHBB →+2.535+1.720<.001<.00132
OVOCIAD1-AS1 →+0.795+1.652<.001.00132
COADRPS10 →-0.505-0.266.002.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,302 associations by consensus.

CBFA2T2 vs HBA2 — OV

Per-sample scatter of CBFA2T2 vs HBA2 in OV (Pearson r = 0.65).

Explore this scatter interactively →

Exploration