CBFA2T2

Across TCGA cell cohorts, CBFA2T2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,030 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CBFA2T2-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with CBFA2T2 in more than 17 cancer types. Because this analysis shows association rather than direction, both CBFA2T2-to-partner and partner-to-CBFA2T2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by CBFA2T2-low versus CBFA2T2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBFA2T2→partner) and Y-score (partner→CBFA2T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.113	+0.995	<.001	<.001	3	18
STOMACH	Regulation of myoblast fusion →	+0.149	+1.510	<.001	<.001	3	17
STOMACH	Negative regulation of myoblast fusion →	+0.105	+1.118	<.001	<.001	3	17
BONE	Regulation of nucleotide-excision repair →	+0.123	+0.968	.001	.002	3	17
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.145	+1.767	<.001	<.001	3	17
STOMACH	Endosomal transport →	+0.092	+1.391	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,030 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by CBFA2T2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →