CBARP

Across TCGA patient cohorts, CBARP protein abundance is significantly associated with the RNA expression of many other genes, with 6,794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CBARP-associated genes across cancer lineages are SPECC1L, SNRPD3, and MAPK1. Each is linked with CBARP in more than 1 cancer types. Because this analysis shows association rather than direction, both CBARP-to-partner and partner-to-CBARP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBARP versus SPECC1L in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBARP→partner) and Y-score (partner→CBARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPECC1L →	+0.361	+0.273	<.001	.002	3	1
GBM	SNRPD3 →	+0.506	+0.345	<.001	<.001	3	1
GBM	MAPK1 →	+0.397	+0.244	<.001	.001	3	1
GBM	SEZ6L →	+2.219	+0.319	<.001	<.001	3	1
GBM	SRRD →	+0.236	+0.206	<.001	<.001	3	1
GBM	PATZ1 →	+0.538	+0.273	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,794 associations by consensus.

CBARP vs SPECC1L — GBM

Explore this scatter interactively →