CBARP

Across TCGA patient cohorts, CBARP mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBARP-associated genes across cancer lineages are Ku80, Annexin-1, and PCNA. Each is linked with CBARP in more than 1 cancer types. Because this analysis shows association rather than direction, both CBARP-to-partner and partner-to-CBARP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by CBARP-low versus CBARP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBARP→partner) and Y-score (partner→CBARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.302	+3.013	.027	.019	3	1
UCEC	Annexin-1 →	+0.652	+3.000	.032	.037	3	1
UCEC	PCNA →	+0.315	+3.000	.011	.037	2	1
UCEC	Shc_pY317 →	-0.237	-3.000	.006	.037	2	1
UCEC	INPP4B →	-0.499	-2.986	.007	.037	1	1
UCEC	Rab25 →	-0.557	-3.000	.003	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Ku80 by CBARP expression — UCEC

Explore this box plot interactively →