CBARP

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CBARP mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CBARP-associated genes across cancer lineages are OR10T2, DPRX, and C11orf97. Each is linked with CBARP in more than 1 cancer types. Because this analysis shows association rather than direction, both CBARP-to-partner and partner-to-CBARP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10T2 grouped by CBARP-low versus CBARP-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBARP→partner) and Y-score (partner→CBARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTOR10T2 →+0.091+3.781<.001.00932
BLOOD_LymphomaDPRX →+0.030+4.867.004.00931
BLOOD_LymphomaC11orf97 →+2.118+5.209<.001.00531
BREASTOR10K2 →+0.031+3.781<.001.00931
BREASTMINAR2 →+0.131+4.386<.001<.00131
LUNG_NSCLC_LUADFGF6 →+0.225+5.228<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

OR10T2 by CBARP expression — BREAST

Box plot of OR10T2 in CBARP-low vs CBARP-high samples in BREAST.

Explore this box plot interactively →

Exploration