CAVIN4

Across TCGA pan-cancer cohorts, CAVIN4 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CAVIN4 data layer compared with 27 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher CAVIN4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CAVIN4 expression acts as an unfavorable survival marker.

BLCA, ACC, and KIRC are the cancer types where CAVIN4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.141	0.687	.003	18	view →
ACC	OS	Median	All	0.285	0.809	.001	15	view →
KIRC	OS	Median	All	0.167	0.655	.038	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CAVIN4–BLCA (OS)

Open the BLCA breakdown →