CAVIN4

Across TCGA patient cohorts, CAVIN4 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAVIN4-associated genes across cancer lineages are ASNS, Di-Ras3, and JNK_pT183_Y185. Each is linked with CAVIN4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAVIN4-to-partner and partner-to-CAVIN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by CAVIN4-low versus CAVIN4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAVIN4→partner) and Y-score (partner→CAVIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.424	+2.321	.005	.034	3	2
UCEC	Di-Ras3 →	-0.140	-2.222	.026	.011	2	3
UCEC	JNK_pT183_Y185 →	-0.178	-3.459	.012	.005	3	1
UCEC	MEK1 →	+0.352	+2.999	.023	.035	3	1
UCEC	PDCD4 →	-0.542	-1.990	.006	.030	3	1
UCEC	Rab25 →	-0.310	-2.321	.027	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

ASNS by CAVIN4 expression — UCEC

Explore this box plot interactively →