CAVIN4

Across TCGA cell cohorts, CAVIN4 mutation is significantly associated with the RNA expression of many other genes, with 271 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAVIN4-associated genes across cancer lineages are CBY1, DESI1, and FZD3. Each is linked with CAVIN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAVIN4-to-partner and partner-to-CAVIN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by CAVIN4-low versus CAVIN4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAVIN4→partner) and Y-score (partner→CAVIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.696	+3.330	<.001	.002	3	1
LARGE_INTESTINE	DESI1 →	+0.642	+3.299	<.001	.004	3	1
LARGE_INTESTINE	FZD3 →	+0.845	+3.212	.001	.006	3	1
LARGE_INTESTINE	CCNP →	+1.388	+3.212	<.001	.006	3	1
LARGE_INTESTINE	C6orf118 →	+0.105	+2.378	<.001	.006	3	1
LARGE_INTESTINE	GUCA1B →	+1.008	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 271 associations by consensus.

CBY1 by CAVIN4 expression — LARGE_INTESTINE

Explore this box plot interactively →