CAVIN2

Across TCGA patient cohorts, CAVIN2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,841 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CAVIN2-associated genes across cancer lineages are FHL5, KLF2, and GPIHBP1. Each is linked with CAVIN2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CAVIN2-to-partner and partner-to-CAVIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAVIN2 versus FHL5 in LSCC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAVIN2→partner) and Y-score (partner→CAVIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FHL5 →	+0.868	+0.444	<.001	<.001	3	10
BRCA	KLF2 →	+1.200	+0.805	<.001	<.001	3	10
CCRCC	GPIHBP1 →	+1.087	+0.530	<.001	<.001	3	10
CCRCC	ASPA →	+1.115	+0.511	.001	.006	3	9
OV	C7 →	+2.453	+0.753	<.001	<.001	3	9
UCEC	RHOJ →	+0.879	+0.832	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,841 associations by consensus.

CAVIN2 vs FHL5 — LSCC

Explore this scatter interactively →