CAVIN1

Across TCGA pan-cancer cohorts, CAVIN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CAVIN1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher CAVIN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CAVIN1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

GBM, PDAC, and LUAD are the cancer types where CAVIN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Median	All	0.609	0.881	<.001	24	view →
PDAC	DFS	Tertile	III,IV	0.212	0.915	.001	9	view →
LUAD	DFS	Median	All	0.826	0.971	.006	6	view →
LSCC	OS	Median	II,III,IV	0.880	1.000	.017	3	view →
HNSC	DFS	Quartile	III,IV	1.000	0.887	.041	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CAVIN1–GBM (DFS)

Open the GBM breakdown →