CAV3

Across TCGA cell cohorts, CAV3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,914 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CAV3-associated GO terms across cancer lineages are Positive regulation of type 2 mitophagy, Regulation of mRNA splicing, via spliceosome, and Nucleic acid transport. Each is linked with CAV3 in more than 7 cancer types. Because this analysis shows association rather than direction, both CAV3-to-partner and partner-to-CAV3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of type 2 mitophagy grouped by CAV3-low versus CAV3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAV3→partner) and Y-score (partner→CAV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of type 2 mitophagy →	+0.098	+0.097	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.075	+0.070	<.001	.001	3	7
SOFT_TISSUE	Nucleic acid transport →	+0.089	+2.175	<.001	<.001	3	7
SOFT_TISSUE	RNA transport →	+0.089	+2.175	<.001	<.001	3	7
SOFT_TISSUE	Regulation of mRNA processing →	+0.114	+2.767	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.045	+0.068	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,914 associations by consensus.

Positive regulation of type 2 mitophagy by CAV3 expression — LIVER

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