CAV2

Across TCGA patient cohorts, CAV2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,367 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAV2-associated genes across cancer lineages are CAV1, JPH2, and CAVIN1. Each is linked with CAV2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CAV2-to-partner and partner-to-CAV2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAV2 versus CAV1 in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAV2→partner) and Y-score (partner→CAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CAV1 →	+1.559	+0.762	<.001	<.001	3	7
COAD	JPH2 →	+1.005	+0.725	<.001	<.001	3	7
BRCA	CAVIN1 →	+1.161	+0.594	<.001	<.001	3	7
OV	TIMP3 →	+1.524	+0.884	<.001	<.001	3	6
OV	EFEMP1 →	+1.636	+0.786	<.001	.001	3	6
BRCA	CALD1 →	+0.910	+0.681	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,367 associations by consensus.

CAV2 vs CAV1 — HNSC

Explore this scatter interactively →