CAV2

Across TCGA patient cohorts, CAV2 mutation is significantly associated with the RNA expression of many other genes, with 286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAV2-associated genes across cancer lineages are TAF9, ZFP91P1, and LINC02340. Each is linked with CAV2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAV2-to-partner and partner-to-CAV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by CAV2-low versus CAV2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAV2→partner) and Y-score (partner→CAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.626	+3.191	<.001	.009	3	1
UCEC	ZFP91P1 →	+0.150	+3.499	.006	.002	3	1
UCEC	LINC02340 →	+0.407	+2.660	.001	.005	3	1
UCEC	RPS29P32 →	+0.599	+2.751	<.001	.002	3	1
UCEC	HNRNPCL3 →	+0.045	+2.345	<.001	.007	3	1
UCEC	PRSS3P3 →	+0.065	+2.790	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 286 associations by consensus.

TAF9 by CAV2 expression — UCEC

Explore this box plot interactively →