CAV1

Across TCGA patient cohorts, CAV1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,992 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAV1-associated proteins across cancer lineages are PXN, CAVIN1, and CAVIN1_S127. Each is linked with CAV1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CAV1-to-partner and partner-to-CAV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAV1 versus PXN in HNSC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAV1→partner) and Y-score (partner→CAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PXN →	+0.335	+0.940	<.001	<.001	3	9
BRCA	CAVIN1 →	+0.936	+1.583	<.001	<.001	3	9
BRCA	CAVIN1_S127 →	+1.187	+1.108	<.001	<.001	3	9
HNSC	EHD1 →	+0.405	+1.115	<.001	.008	3	9
GBM	VIM →	+0.570	+1.573	<.001	<.001	3	8
BRCA	CAVIN3 →	+0.904	+1.485	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,992 associations by consensus.

CAV1 vs PXN — HNSC

Explore this scatter interactively →