CAV1

Across TCGA patient cohorts, CAV1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,751 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAV1-associated genes across cancer lineages are CAV2, KANK2, and MYLK. Each is linked with CAV1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CAV1-to-partner and partner-to-CAV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAV1 versus CAV2 in GBM, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAV1→partner) and Y-score (partner→CAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CAV2 →	+1.434	+1.223	<.001	<.001	3	9
BRCA	KANK2 →	+0.851	+0.783	<.001	<.001	3	9
UCEC	MYLK →	+1.294	+0.891	<.001	<.001	3	9
COAD	CAVIN1 →	+1.160	+0.673	<.001	<.001	3	9
OV	PMP22 →	+0.820	+0.673	<.001	<.001	3	8
BRCA	CNRIP1 →	+0.859	+0.814	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,751 associations by consensus.

CAV1 vs CAV2 — GBM

Explore this scatter interactively →