CAV1

Across TCGA patient cohorts, CAV1 mutation is significantly associated with the RNA expression of many other genes, with 2,976 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAV1-associated genes across cancer lineages are RNU1-17P, LINC01072, and RNA5SP198. Each is linked with CAV1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAV1-to-partner and partner-to-CAV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by CAV1-low versus CAV1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAV1→partner) and Y-score (partner→CAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU1-17P →	+0.578	+5.435	<.001	.005	3	3
HNSC	LINC01072 →	+0.125	+5.241	<.001	.007	3	3
CESC	RNA5SP198 →	+0.241	+4.559	<.001	.006	3	2
CESC	RPS24P1 →	+0.057	+4.984	<.001	.003	3	2
HNSC	MIR4510 →	+0.601	+6.468	<.001	.001	3	2
LUAD	RPS12P15 →	+0.163	+5.343	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,976 associations by consensus.

RNU1-17P by CAV1 expression — HNSC

Explore this box plot interactively →