CAV1

Across TCGA cell cohorts, CAV1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,270 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CAV1-associated GO terms across cancer lineages are Positive regulation of gap junction assembly, Regulation of coagulation, and Endocytosis involved in viral entry into host cell. Each is linked with CAV1 in more than 16 cancer types. Because this analysis shows association rather than direction, both CAV1-to-partner and partner-to-CAV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of gap junction assembly grouped by CAV1-low versus CAV1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAV1→partner) and Y-score (partner→CAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of gap junction assembly →	+1.427	+2.660	<.001	<.001	3	17
SOFT_TISSUE	Regulation of coagulation →	+0.187	+3.979	<.001	<.001	3	16
SOFT_TISSUE	Endocytosis involved in viral entry into host cell →	+0.169	+4.161	<.001	<.001	3	16
LIVER	Positive regulation of calcium ion transport into cytosol →	+0.414	+4.804	<.001	<.001	3	15
BREAST	Regulation of hemostasis →	+0.206	+5.501	<.001	<.001	3	15
BREAST	Receptor-mediated endocytosis of virus by host cell →	+0.254	+4.575	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,270 associations by consensus.

Positive regulation of gap junction assembly by CAV1 expression — BLOOD_Lymphoma

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