Across TCGA patient cohorts, CATSPERZ mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPERZ-associated genes across cancer lineages are IGHD1-26, RNU6-99P, and NTAN1P1. Each is linked with CATSPERZ in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPERZ-to-partner and partner-to-CATSPERZ results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERZ→partner) and Y-score (partner→CATSPERZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHD1-26 →	+1.277	+4.484	<.001	.009	3	2
SKCM	RNU6-99P →	+0.463	+7.816	<.001	.008	3	2
UCEC	NTAN1P1 →	+0.163	+4.937	.006	.005	3	1
UCEC	RN7SL726P →	+0.362	+5.073	<.001	.001	3	1
UCEC	MIR6766 →	+1.005	+5.943	<.001	<.001	3	1
UCEC	SPATA48 →	+0.155	+4.606	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

CATSPERZ survival (RNA) · tumor vs normal (RNA) · all CATSPERZ data types