CATSPERG

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CATSPERG mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CATSPERG data layer compared with 26 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CATSPERG mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CATSPERG expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and LSCC are the cancer types where CATSPERG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianAll1.0000.902.03824view →
CCRCCDFSMedianIII,IV0.8130.521.01018view →
LSCCDFSMedianAll0.9280.681.00814view →
LUADDFSTertileIII,IV0.9160.375.0248view →
HNSCDFSMedianIII,IV0.4690.732.0236view →
PDACDFSTertileII,III,IV0.3040.520.0412view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CATSPERG–COAD (DFS)

Kaplan–Meier survival curve for CATSPERG mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration