CATSPERG

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CATSPERG mutation is significantly associated with the RNA expression of many other genes, with 3,271 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPERG-associated genes across cancer lineages are RN7SL294P, RNU6-637P, and MIR5007. Each is linked with CATSPERG in more than 2 cancer types. Because this analysis shows association rather than direction, both CATSPERG-to-partner and partner-to-CATSPERG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL294P grouped by CATSPERG-low versus CATSPERG-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERG→partner) and Y-score (partner→CATSPERG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SL294P →+0.022+4.228<.001.00433
STADRNU6-637P →+0.446+3.465<.001.00633
STADMIR5007 →+0.286+3.267.004.00933
LUADRNU6-1067P →+2.196+5.712<.001.00333
READMTCO2P24 →+0.293+5.219<.001.00632
PRADRNU6-187P →+0.318+7.939<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,271 associations by consensus.

RN7SL294P by CATSPERG expression — SKCM

Box plot of RN7SL294P in CATSPERG-low vs CATSPERG-high samples in SKCM.

Explore this box plot interactively →

Exploration