CATSPERG

Across TCGA patient cohorts, CATSPERG mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPERG-associated genes across cancer lineages are ASNS, PEA-15_pS116, and PI3K-p110-a. Each is linked with CATSPERG in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPERG-to-partner and partner-to-CATSPERG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by CATSPERG-low versus CATSPERG-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERG→partner) and Y-score (partner→CATSPERG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ASNS →	+0.383	+2.700	.049	.006	3	2
UCEC	PEA-15_pS116 →	+0.313	+1.906	.005	.014	3	2
UCEC	PI3K-p110-a →	-0.117	-2.087	.037	.005	3	2
UCEC	Chk2 →	-0.160	-1.584	.032	.017	3	2
BLCA	HSP70 →	-0.509	-3.000	.030	.036	3	1
SKCM	CD49b →	+0.306	+3.000	.003	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

ASNS by CATSPERG expression — SKCM

Explore this box plot interactively →