CATSPERG

Across TCGA cell cohorts, CATSPERG mutation is significantly associated with the RNA expression of many other genes, with 512 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CATSPERG-associated genes across cancer lineages are OR10R2, GDF2, and OR6B3. Each is linked with CATSPERG in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPERG-to-partner and partner-to-CATSPERG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by CATSPERG-low versus CATSPERG-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERG→partner) and Y-score (partner→CATSPERG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10R2 →	+0.913	+4.269	.001	.005	3	2
LUNG_SCLC	GDF2 →	+0.017	+4.643	<.001	.004	3	2
BONE	OR6B3 →	+2.126	+5.169	<.001	.004	3	1
LUNG_SCLC	OR10T2 →	+0.136	+4.044	.004	.009	3	1
LUNG_SCLC	OR11G2 →	+0.022	+4.643	<.001	.004	3	1
LUNG_NSCLC_LUSC	MYOD1 →	+0.046	+4.108	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 512 associations by consensus.

OR10R2 by CATSPERG expression — LUNG_SCLC

Explore this box plot interactively →