CATSPERE

Across TCGA pan-cancer cohorts, CATSPERE Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CATSPERE data layer compared with 23 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CATSPERE Mutation is associated with better overall survival. In most high-consensus cancer types, elevated CATSPERE expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, KIRP, and SARC are the cancer types where CATSPERE Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.893	0.515	.008	18	view →
KIRP	DFS	Median	All	0.277	0.867	.004	6	view →
SARC	OS	Median	All	0.162	0.767	.002	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CATSPERE–UCEC (OS)

Open the UCEC breakdown →