CATSPERE

Across TCGA cell cohorts, CATSPERE mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CATSPERE-associated genes across cancer lineages are OPN1LW, DKK4, and C9. Each is linked with CATSPERE in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPERE-to-partner and partner-to-CATSPERE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1LW grouped by CATSPERE-low versus CATSPERE-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERE→partner) and Y-score (partner→CATSPERE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	OPN1LW →	+0.020	+4.643	<.001	.008	3	1
BLOOD_Leukemia	DKK4 →	+0.151	+4.108	.003	<.001	3	1
BLOOD_Leukemia	C9 →	+0.939	+2.807	<.001	.008	3	1
BLOOD_Leukemia	OLFM3 →	+0.769	+3.697	<.001	.002	3	1
BLOOD_Leukemia	VSX2 →	+0.021	+3.258	.002	.007	3	1
BLOOD_Leukemia	ASZ1 →	+0.089	+3.304	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

OPN1LW by CATSPERE expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →