CATSPER2

Across TCGA patient cohorts, CATSPER2 mutation is significantly associated with the RNA expression of many other genes, with 4,169 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPER2-associated genes across cancer lineages are RN7SKP139, C19orf54, and NANOGP10. Each is linked with CATSPER2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CATSPER2-to-partner and partner-to-CATSPER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP139 grouped by CATSPER2-low versus CATSPER2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPER2→partner) and Y-score (partner→CATSPER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SKP139 →	+0.346	+4.859	<.001	.004	3	3
UCEC	C19orf54 →	+0.401	+2.288	<.001	<.001	3	3
CESC	NANOGP10 →	+0.054	+5.306	<.001	.006	3	3
BLCA	MTND4P33 →	+0.033	+4.314	<.001	.009	3	3
BLCA	RN7SL687P →	+0.756	+3.642	<.001	.009	3	2
SKCM	KLC2 →	+0.589	+3.233	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,169 associations by consensus.

RN7SKP139 by CATSPER2 expression — LUAD

Explore this box plot interactively →