CATSPER2

Across TCGA cell cohorts, CATSPER2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,064 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CATSPER2-associated GO terms across cancer lineages are mRNA splice site recognition, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Viral translational termination-reinitiation. Each is linked with CATSPER2 in more than 13 cancer types. Because this analysis shows association rather than direction, both CATSPER2-to-partner and partner-to-CATSPER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by CATSPER2-low versus CATSPER2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPER2→partner) and Y-score (partner→CATSPER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.156	+1.347	<.001	<.001	3	14
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.156	+0.945	<.001	<.001	3	13
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.085	+1.184	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.100	-0.873	.002	.005	3	13
URINARY_TRACT	Cilium-dependent cell motility →	-0.083	-1.169	.001	.002	3	13
URINARY_TRACT	Cilium or flagellum-dependent cell motility →	-0.083	-1.169	.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,064 associations by consensus.

mRNA splice site recognition by CATSPER2 expression — UPPER_AERODIGESTIVE_TRACT

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