CATSPER2

Across TCGA cell cohorts, CATSPER2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CATSPER2-associated genes across cancer lineages are TEX26, IL31, and C3orf56. Each is linked with CATSPER2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPER2-to-partner and partner-to-CATSPER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX26 grouped by CATSPER2-low versus CATSPER2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPER2→partner) and Y-score (partner→CATSPER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TEX26 →	+0.035	+5.228	<.001	.005	3	1
SKIN	IL31 →	+0.028	+4.977	<.001	.007	3	1
SKIN	C3orf56 →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Leukemia	OR51T1 →	+0.126	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR4A47 →	+0.022	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TEX26 by CATSPER2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →