CATIP

Across TCGA pan-cancer cohorts, CATIP Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CATIP data layer compared with 20 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CATIP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CATIP expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUSC, BLCA, and LIHC are the cancer types where CATIP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.178	0.762	.003	24	view →
BLCA	OS	Median	All	0.198	0.722	<.001	18	view →
LIHC	OS	Median	II,III,IV	0.130	0.622	.002	12	view →
UCEC	DFS	Median	All	1.000	0.631	.036	10	view →
LUAD	DFS	Median	All	0.049	0.814	<.001	6	view →
SKCM	OS	Median	IV	0.415	0.861	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CATIP–LUSC (OS)

Open the LUSC breakdown →