CATIP-AS2

Across TCGA pan-cancer cohorts, CATIP-AS2 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CATIP-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CATIP-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types CATIP-AS2 is over-expressed in tumor, although a few such as KIRP and THCA show the opposite, repressed pattern.

KIRP, THCA, and KIRC are the cancer types where CATIP-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CATIP-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	IV	−2.177	<.001	11	view →
THCA	Male	III,IV	−1.600	<.001	11	view →
KIRC	Female	II,III,IV	−1.180	<.001	11	view →
HNSC	All	All	+0.135	<.001	11	view →
KICH	Female	All	−1.668	<.001	8	view →
STAD	All	All	+0.561	<.001	6	view →
LUSC	All	All	−0.294	<.001	6	view →
BRCA	Female	II,III,IV	+0.190	<.001	6	view →
BLCA	Female	All	+0.222	.026	4	view →
LIHC	Male	All	+0.181	.031	2	view →
LUAD	Male	III,IV	−0.435	.031	1	view →
COAD	All	All	+0.101	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CATIP-AS2–KIRP

Open the KIRP breakdown →