CAT

Across TCGA patient cohorts, CAT protein abundance is significantly associated with the RNA expression of many other genes, with 2,971 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAT-associated genes across cancer lineages are PDK1, ZSCAN31, and UNC119B. Each is linked with CAT in more than 2 cancer types. Because this analysis shows association rather than direction, both CAT-to-partner and partner-to-CAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAT versus PDK1 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAT→partner) and Y-score (partner→CAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PDK1 →	+0.930	+0.350	<.001	.002	3	3
HNSC	ZSCAN31 →	-0.923	-0.471	.002	<.001	3	3
BRCA	UNC119B →	-0.568	-0.601	.005	<.001	3	3
CCRCC	LIVAR →	-0.680	-0.254	<.001	<.001	3	3
CCRCC	IMMP1LP1 →	+0.671	+0.360	<.001	<.001	3	3
CCRCC	SLC10A1 →	-0.877	-0.362	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,971 associations by consensus.

CAT vs PDK1 — HNSC

Explore this scatter interactively →