CAT

Across TCGA cell cohorts, CAT protein abundance is significantly associated with the RNA expression of many other genes, with 4,339 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAT-associated genes across cancer lineages are VDR, TST, and CHN1. Each is linked with CAT in more than 5 cancer types. Because this analysis shows association rather than direction, both CAT-to-partner and partner-to-CAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAT versus VDR in BLOOD_Leukemia, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAT→partner) and Y-score (partner→CAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	VDR →	+1.944	+2.096	<.001	<.001	3	6
BLOOD_Leukemia	TST →	+2.904	+1.797	<.001	<.001	3	6
BLOOD_Leukemia	CHN1 →	-1.501	-1.739	<.001	<.001	3	6
BREAST	ANK2 →	-1.061	-0.986	.003	.003	3	5
BLOOD_Leukemia	TALDO1 →	+0.548	+1.386	<.001	<.001	3	5
LARGE_INTESTINE	PPARG →	+1.536	+1.280	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,339 associations by consensus.

CAT vs VDR — BLOOD_Leukemia

Explore this scatter interactively →