CASTOR1

Across TCGA pan-cancer cohorts, CASTOR1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CASTOR1 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CASTOR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CASTOR1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD and CCRCC are the cancer types where CASTOR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.327	1.000	.008	21	view →
CCRCC	OS	Quartile	All	1.000	0.674	.038	5	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CASTOR1–LUAD (DFS)

Open the LUAD breakdown →