CASQ2

Across TCGA patient cohorts, CASQ2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,799 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CASQ2-associated genes across cancer lineages are RECK, RSPO3, and EMCN. Each is linked with CASQ2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CASQ2-to-partner and partner-to-CASQ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASQ2 versus RECK in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASQ2→partner) and Y-score (partner→CASQ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RECK →	+0.977	+1.653	.001	.002	3	3
COAD	RSPO3 →	+1.064	+0.856	<.001	<.001	3	3
CCRCC	EMCN →	+2.070	+1.173	.007	.007	3	3
CCRCC	CSDC2 →	+2.491	+1.173	.002	.007	3	3
COAD	PGM5-AS1 →	+0.758	+0.930	<.001	<.001	3	3
LUAD	LYL1 →	+0.665	+0.865	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,799 associations by consensus.

CASQ2 vs RECK — OV

Explore this scatter interactively →