CASQ2

Across TCGA cell cohorts, CASQ2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CASQ2-associated genes across cancer lineages are GP9 and TCP10L2. Each is linked with CASQ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CASQ2-to-partner and partner-to-CASQ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GP9 grouped by CASQ2-low versus CASQ2-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASQ2→partner) and Y-score (partner→CASQ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	GP9 →	+0.049	+5.169	<.001	.004	3	2
LUNG_NSCLC_LUAD	TCP10L2 →	+0.074	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GP9 by CASQ2 expression — BONE

Explore this box plot interactively →