CASQ1

Across TCGA cell cohorts, CASQ1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CASQ1-associated genes across cancer lineages are OR9K2 and OR4A47. Each is linked with CASQ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CASQ1-to-partner and partner-to-CASQ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9K2 grouped by CASQ1-low versus CASQ1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASQ1→partner) and Y-score (partner→CASQ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR9K2 →	+0.030	+6.022	<.001	.001	3	1
LARGE_INTESTINE	OR4A47 →	+0.030	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR9K2 by CASQ1 expression — LARGE_INTESTINE

Explore this box plot interactively →