CASQ1

Across TCGA cell cohorts, CASQ1 mutation is significantly associated with the mutation status of many other genes, with 811 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CASQ1-associated genes across cancer lineages are ACSL6, TARS2, and IQSEC1. Each is linked with CASQ1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CASQ1-to-partner and partner-to-CASQ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACSL6 grouped by CASQ1-low versus CASQ1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASQ1→partner) and Y-score (partner→CASQ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ACSL6 →	+4.584	+4.584	.007	.007	1	3
BLOOD_Lymphoma	TARS2 →	+5.584	+5.014	.003	.003	1	2
BLOOD_Lymphoma	IQSEC1 →	+4.584	+4.584	.007	.007	1	2
BLOOD_Lymphoma	MTA2 →	+5.584	+5.014	.003	.003	1	2
BLOOD_Lymphoma	FZD7 →	+4.584	+4.584	.007	.007	1	2
BLOOD_Lymphoma	WASF2 →	+5.584	+5.014	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 811 associations by consensus.

ACSL6 by CASQ1 expression — BLOOD_Lymphoma

Explore this box plot interactively →