CASP7

Across TCGA patient cohorts, CASP7 protein abundance is significantly associated with the RNA expression of many other genes, with 10,959 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CASP7-associated genes across cancer lineages are OASL, B2M, and PSMB10. Each is linked with CASP7 in more than 5 cancer types. Because this analysis shows association rather than direction, both CASP7-to-partner and partner-to-CASP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASP7 versus OASL in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP7→partner) and Y-score (partner→CASP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OASL →	+1.734	+0.341	<.001	<.001	3	6
GBM	B2M →	+0.922	+0.628	<.001	<.001	3	6
HNSC	PSMB10 →	+1.017	+0.442	<.001	<.001	3	6
UCEC	ACSL5 →	+1.118	+0.298	.006	.007	3	5
OV	UBAC2-AS1 →	-0.631	-0.440	<.001	.002	3	5
OV	APOL3 →	+1.274	+0.447	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,959 associations by consensus.

CASP7 vs OASL — HNSC

Explore this scatter interactively →