CASP6

Across TCGA patient cohorts, CASP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,344 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CASP6-associated proteins across cancer lineages are SEC24B, MEF2C_S396, and GSTCD. Each is linked with CASP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CASP6-to-partner and partner-to-CASP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASP6 versus SEC24B in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP6→partner) and Y-score (partner→CASP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEC24B →	+0.204	+0.620	<.001	<.001	3	5
LSCC	MEF2C_S396 →	-0.400	-0.312	<.001	.001	3	4
BRCA	GSTCD →	+0.309	+0.497	<.001	<.001	3	4
BRCA	ARFIP1 →	+0.331	+0.424	<.001	.003	2	5
BRCA	RABL6 →	+0.329	+0.525	<.001	<.001	3	3
BRCA	INPP4B →	+0.976	+0.502	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,344 associations by consensus.

CASP6 vs SEC24B — OV

Explore this scatter interactively →