CASP4LP

Across TCGA pan-cancer cohorts, CASP4LP Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CASP4LP data layer compared with 26 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher CASP4LP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CASP4LP expression acts as an unfavorable survival marker.

THYM and LUAD are the cancer types where CASP4LP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
LUAD	OS	Median	All	0.258	0.812	.004	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CASP4LP–THYM (OS)

Open the THYM breakdown →