CASP4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CASP4 mutation is significantly associated with the RNA expression of many other genes, with 2,765 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CASP4-associated genes across cancer lineages are RN7SL705P, HIRAP1, and MEMO1P3. Each is linked with CASP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CASP4-to-partner and partner-to-CASP4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP4→partner) and Y-score (partner→CASP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRN7SL705P →+0.531+6.584<.001.00133
LUADHIRAP1 →+0.156+6.444<.001.00133
LIHCMEMO1P3 →+0.160+5.355<.001.00532
LIHCLINC02030 →+0.029+5.186.008.00732
LUADRNU2-14P →+0.445+6.197<.001.00132
LUADLINC01941 →+0.155+5.157<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,765 associations by consensus.

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