CASP1P1

Across TCGA patient cohorts, CASP1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,560 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible CASP1P1-associated GO terms across cancer lineages are Regulation of DNA repair, Methylation, and Cell cycle G2/M phase transition. Each is linked with CASP1P1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CASP1P1-to-partner and partner-to-CASP1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by CASP1P1-low versus CASP1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP1P1→partner) and Y-score (partner→CASP1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.032	+0.084	.004	<.001	3	7
STAD	Methylation →	+0.028	+0.091	.006	<.001	3	6
LUAD	Cell cycle G2/M phase transition →	+0.043	+0.056	<.001	.001	3	6
STAD	Intracellular protein transmembrane transport →	+0.030	+0.079	.009	<.001	3	5
STAD	Regulation of DNA binding →	+0.034	+0.096	.001	<.001	3	5
STAD	Nuclear export →	+0.035	+0.133	.006	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,560 associations by consensus.

Regulation of DNA repair by CASP1P1 expression — STAD

Explore this box plot interactively →